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Caution should be exercised when other potent cytochrome P450 3A4 inhibitors are coadministered with fluticasone propionate. Advise patient to report the following symptoms to health care provider: fluticasone pharmacy sneezing, nasal irritation, nosebleed. Pediatric patients may be more susceptible to systemic toxicity from equivalent doses due to their larger skin surface to body mass ratios see PRECAUTIONS: Pediatric Use.